Sildenafil, bought as the brand name title Viagra between Many others, is really a medication employed to deal with erectile dysfunction and pulmonary arterial hypertension.[three] Its success for treating sexual dysfunction in Ladies has not been demonstrated.[three]
Sildenafil should not be taken by folks who get nitrates such as nitroglycerin (glycerin trinitrate), as this will likely result in a critical and probably lethal drop in hypertension.
In the United States, Pfizer acquired two patents for sildenafil: a person for its indication to deal with heart problems (promoted as Revatio) and Yet another for its sign to take care of erectile dysfunction (marketed as Viagra). The material is similar less than each trade names.
Get in touch with your health practitioner or seek emergency medical awareness In case your erection is agonizing or lasts longer than 4 hrs. A prolonged erection (priapism) can injury the penis.
The principal indication of sildenafil is therapy of erectile dysfunction (inability to sustain a satisfactory erection to accomplish intercourse).
The health data contained herein is delivered for academic applications only and is not meant to replace discussions which has a healthcare company. All decisions relating to affected individual care need to be made using a Health care provider, taking into consideration the one of a kind qualities with the patient.
Sildenafil is in a category of prescription drugs identified as phosphodiesterase (PDE) inhibitors. Sildenafil treats erectile dysfunction by expanding blood move into the penis all through sexual stimulation. This amplified blood move could potentially cause an erection. Sildenafil treats PAH by enjoyable the blood vessels from the lungs to permit blood to stream simply.
Your health practitioner can generate a prescription for single packs or you are able to question your pharmacist for them any time you fill your prescription.
Sildenafil is damaged down inside the liver by hepatic metabolism applying cytochrome p450 enzymes, mostly CYP450 3A4(important route), but in addition by CYP2C9 (minor route) hepatic isoenzymes. The key product of metabolisation by these enzymes is N-desmethylated sildenafil, that's metabolised additional. This metabolite also has an affinity for that PDE receptors, about 40% of that of sildenafil. As a result, the metabolite is responsible for about twenty% of sildenafil's motion.
Sildenafil may possibly result in other Unwanted side effects. Connect with your health practitioner For those who have any unusual complications when you are taking this medication.
Also, Adult men having VIAGRA confirmed an advancement in their capability to get and preserve an erection as opposed to people that took placebo.
In the event you working experience a unexpected loss of eyesight while you are getting sildenafil, contact your health care provider right away. Do not just click here take any more doses of sildenafil or very similar medicines for instance tadalafil (Cialis) or vardenafil (Levitra) until finally you check with your medical doctor.
Tentative proof implies that sildenafil may aid Adult men who experience antidepressant-induced erectile dysfunction. Pulmonary hypertension
Maintain this medication from the container it came in, tightly shut, and out of get to of youngsters. Retailer the tablets at home temperature and far from surplus heat and dampness (not in the lavatory).